BDBM659662 7-((6-((4-chlorobenzyl)oxy)-S-methoxypyridin-3-yl)oxy)-3-methyl-4H-pyrido[1,2-a]pyrimidin-4-one::US20240092774, Compound 19

SMILES COc1cc(Oc2ccc3ncc(C)c(=O)n3c2)cnc1OCc1ccc(Cl)cc1

InChI Key InChIKey=LMQYKZQEYXMQEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 659662   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM659662(7-((6-((4-chlorobenzyl)oxy)-S-methoxypyridin-3-yl)...)
Affinity DataIC50: 5nMAssay Description:Methods: 1) Kinase Reaction (10 μL System)2.5 μL of 4× test compound was added to each reaction well of the 384 plate, and the correspondin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent