BDBM660132 (E)-3-(3-(8-Oxa-3-azabicyclo[3.2.1]octan-3-yl)-3-oxoprop-1-en-1-yl)-N-cyclopropyl-7-hydroxy-4-isobutyl-2-methyl-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-6-carboxamide::US20240092784, Example 569

SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CC4CCC(C3)O4)c(C)nn2c(O)c(C(=O)NC2CC2)c1=O

InChI Key InChIKey=HTPBLPNOUFVTBN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 660132   

TargetSepiapterin reductase(Human)
Nissan Chemical

US Patent
LigandPNGBDBM660132((E)-3-(3-(8-Oxa-3-azabicyclo[3.2.1]octan-3-yl)-3-o...)
Affinity DataIC50: 0.670nMAssay Description:Human SPR inhibitory activity was measured by using a 384-well low adsorption clear plate (Greiner) with buffer D containing 100 mM Tris-HCl (pH 7.5)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent