BDBM660859 N1-(6-chloropyridin-3-yl)-N6- ((3-methyloxetan-3- yl)methyl)isoquinoline-1,6- diamine::US20240101531, Example 245

SMILES CC1(CNc2ccc3c(Nc4ccc(Cl)nc4)nccc3c2)COC1

InChI Key InChIKey=UCGKLHWZEXNFGM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 660859   

TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660859(N1-(6-chloropyridin-3-yl)-N6- ((3-methyloxetan-3- ...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent