BDBM661101 (2S)-3-(4-methoxyphenyl)-2-[4-[(1S)-1-[[5-(2-pyridyl)-2-thienyl]sulfonylamino]ethyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 47

SMILES COc1ccc(C[C@@H](C(=O)NO)n2cc(nn2)[C@H](C)NS(=O)(=O)c2ccc(s2)-c2ccccn2)cc1

InChI Key InChIKey=LDEVRVSSIRYXOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661101   

TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Human)
Universite De Lille

US Patent
LigandPNGBDBM661101(US20240101542, Compound 47 | (2S)-3-(4-methoxyphen...)
Affinity DataIC50: 500nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent