BDBM661108 (2S)-3-(4-ethynylphenyl)-2-[4-[[(5-phenyl-2-thienyl)sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 54

SMILES ONC(=O)[C@H](Cc1ccc(cc1)C#C)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccc2)nn1

InChI Key InChIKey=GNRYGLXPVKEJQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661108   

TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Human)
Universite De Lille

US Patent
LigandPNGBDBM661108(US20240101542, Compound 54 | (2S)-3-(4-ethynylphen...)
Affinity DataIC50: 500nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetEndoplasmic reticulum aminopeptidase 2(Human)
Universite De Lille

US Patent
LigandPNGBDBM661108(US20240101542, Compound 54 | (2S)-3-(4-ethynylphen...)
Affinity DataIC50: 5.00E+3nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent