BDBM661181 2-(4-(4-methyl-4H-1,2,4-triazol-3- yl)piperidin-1-yl)-3-(6- methylpyridazin-4-yl)-6-(1H-pyrazol-3- yl)benzonitrile::US20240101544, Example 65

SMILES Cc1cc(-c2ccc(-c3cc[nH]n3)c(C#N)c2N2CCC(c3nncn3C)CC2)cnn1

InChI Key InChIKey=UPBJLEDVOONZQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661181   

TargetGlutaminyl-peptide cyclotransferase(Human)
858 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 661181BDBM661181(US20240101544, Example 65 | 2-(4-(4-methyl-4H-1,2,...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCT (rhQPCT, R&D Systems) activity were determined using a biochemical fluorescent-based assay. QPCT acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
858 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 661181BDBM661181(US20240101544, Example 65 | 2-(4-(4-methyl-4H-1,2,...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCTL activity were determined using a biochemical fluorescent-based assay. QPCTL activity was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent