BDBM661904 (2R,3R,4S,5R)-2- {4-amino-5-bromo- 7H-pyrrolo[2,3- d]pyrimidin-7-yl}- 5-[(1E)-5- [(cyclobutylmethyl) amino]pent-1-en-1-::US20240101589, Example 2

SMILES Nc1ncnc2n(cc(Br)c12)[C@@H]1O[C@H](\C=C\CCCNCC2CCC2)[C@@H](O)[C@H]1O

InChI Key InChIKey=FSMVOBUDPCUEOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661904   

LigandPNGBDBM661904((2R,3R,4S,5R)-2- {4-amino-5-bromo- 7H-pyrrolo[2,3-...)
Affinity DataIC50: 42.6nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2024
Entry Details
US Patent