BDBM661910 (2R,3R,4S,5R)-2- {4-amino-5-bromo- 7H-pyrrolo[2,3- d]pyrimidin-7-yl}-5- [(1E)-5-aminopent- 1-en-1-yl]oxolane-::US20240101589, Example 8

SMILES NCCC\C=C\[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Br)c2c(N)ncnc12

InChI Key InChIKey=JWHLLJDYOCMKNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661910   

LigandPNGBDBM661910((2R,3R,4S,5R)-2- {4-amino-5-bromo- 7H-pyrrolo[2,3-...)
Affinity DataIC50: 505nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2024
Entry Details
US Patent