BDBM661931 (1R,2S,3R,5R)-3- {4-amino-5-fluoro- 7H-pyrrolo[2,3- d]pyrimidin-7-yl}-5- (2-{[{{3- fluorobicyclo[1.1.1] pentan-1- yl}methyl)amino] methyl}-1H-indol-6- yl)cyclopentane-1,2-diol::US20240101589, Example 29

SMILES Nc1ncnc2n(cc(F)c12)[C@@H]1C[C@@H]([C@@H](O)[C@H]1O)c1ccc2cc(CNCC34CC(F)(C3)C4)[nH]c2c1

InChI Key InChIKey=WICOOAQKXZHDEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661931   

LigandPNGBDBM661931((1R,2S,3R,5R)-3- {4-amino-5-fluoro- 7H-pyrrolo[2,3...)
Affinity DataIC50: 6.10nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2024
Entry Details
US Patent