BDBM661935 (1R,2S,3R,5R)-3- {4-amino-5-bromo- 7H-pyrrolo[2,3- d]pyrimidin-7-yl}-5- (2-{[{{3- fluorobicyclo[1.1.1]::US20240101589, Example 31

SMILES Nc1ncnc2n(cc(Br)c12)[C@@H]1C[C@@H]([C@@H](O)[C@H]1O)c1ccc2[nH]c(CNCC34CC(F)(C3)C4)cc2c1

InChI Key InChIKey=SZFMMALFCILUJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661935   

LigandPNGBDBM661935((1R,2S,3R,5R)-3- {4-amino-5-bromo- 7H-pyrrolo[2,3-...)
Affinity DataIC50: 8.24nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2024
Entry Details
US Patent