BDBM661940 3-{4-amino-5-bromo- 7H-pyrrolo[2,3- d]pyrimidin-7-yl}-5- [3-({6-azaspiro[3.4]octan-6- yl}methyl)phenyl] cyclopentane-1,2-diol::US20240101589, Example 38

SMILES Nc1ncnc2n(cc(Br)c12)[C@@H]1C[C@@H]([C@@H](O)[C@H]1O)c1cccc(CN2CCC3(CCC3)C2)c1

InChI Key InChIKey=GRQXAJFOQGYYAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661940   

LigandPNGBDBM661940(3-{4-amino-5-bromo- 7H-pyrrolo[2,3- d]pyrimidin-7-...)
Affinity DataIC50: 2.64E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2024
Entry Details
US Patent