BDBM661942 3-[(1R,2R,3S,4R)- 4-{4-amino-5- bromo-7H-pyrrolo[2,3- d]pyrimidin-7-yl}-2,3- dihydroxycyclopentyl]- N-({3-fluorobicyclo[1.1.1] pentan-1- yl}methyl)benzamide::US20240101589, Example 40

SMILES Nc1ncnc2n(cc(Br)c12)[C@@H]1C[C@@H]([C@@H](O)[C@H]1O)c1cccc(c1)C(=O)NCC12CC(F)(C1)C2

InChI Key InChIKey=RVKUZAWXFKTOAP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661942   

LigandPNGBDBM661942(3-[(1R,2R,3S,4R)- 4-{4-amino-5- bromo-7H-pyrrolo[2...)
Affinity DataIC50: 7.93E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
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Date in BDB:
6/12/2024
Entry Details
US Patent