BDBM661978 (S)-4-(6-(2,3-dihydrobenzo[b][1,4]dioxin- 6-yl)-3-(pyrrolidin-3-ylmethyl)-3H- imidazo[4,5-c]pyridin-7-yl)-2- fluorobenzonitrile::US11944614, Compound 28

SMILES Fc1cc(ccc1C#N)-c1c(ncc2n(C[C@H]3CCNC3)cnc12)-c1ccc2OCCOc2c1

InChI Key InChIKey=QVIZMOHYNKHBLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661978   

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandPNGBDBM661978((S)-4-(6-(2,3-dihydrobenzo[b][1,4]dioxin- 6-yl)-3-...)
Affinity DataIC50: 9.57nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent