BDBM662058 2-chloro-N-(4-((E)-2-(2-(((1r,4r)-4- (dimethylamino)cyclohexyl)amino)pyrimidin- 5-yl)vinyl)-2-fluoro-3- methoxyphenyl)benzenesulfonamide::US11945784, Compound 66
SMILES COc1c(F)c(NS(=O)(=O)c2ccccc2Cl)ccc1\C=C\c1cnc(NC2CC[C@@H](CC2)N(C)C)nc1
InChI Key InChIKey=OUFOUARAFUQINT-DKTHLVHBSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 662058
Affinity DataIC50: <1nMAssay Description:In vitro FRET assay was performed to evaluate the ability of select compounds to inhibit IRE1, the results of which are summarized in Table 3. To per...More data for this Ligand-Target Pair