BDBM662062 Methyl 1-(bis(4-fluorophenyl)methyl)-4-(6-cyano-1-methyl-2-oxo-1,2-dihydro-1,5-naphthyridin-4-yl)piperazine-2-carboxylate::US20240108654, Compound 2

SMILES COC(=O)C1CN(CCN1C(c1ccc(F)cc1)c1ccc(F)cc1)c1cc(=O)n(C)c2ccc(nc12)C#N

InChI Key InChIKey=NVWKZBCWVDIOOZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 662062   

TargetDiacylglycerol kinase zeta(Human)
Juno Therapeutics

US Patent
LigandPNGBDBM662062(Methyl 1-(bis(4-fluorophenyl)methyl)-4-(6-cyano-1-...)
Affinity DataIC50: 1.70E+3nMAssay Description:The DGKα and DGKζ reactions were performed using either extruded liposome (DGKα and DGKζ LIPGLO assays) or detergent/lipid micell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Juno Therapeutics

US Patent
LigandPNGBDBM662062(Methyl 1-(bis(4-fluorophenyl)methyl)-4-(6-cyano-1-...)
Affinity DataIC50: 2.40E+5nMAssay Description:The DGKα and DGKζ reactions were performed using either extruded liposome (DGKα and DGKζ LIPGLO assays) or detergent/lipid micell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent