BDBM662069 8-[(2S,5R)-4-[(4-fluorophenyl)(4-methylphenyl)methyl]-2,5-dimethylpiperazin-1-yl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile::US20240108654, Compound 10

SMILES C[C@@H]1CN([C@@H](C)CN1C(c1ccc(C)cc1)c1ccc(F)cc1)c1cc(=O)n(C)c2ccc(nc12)C#N

InChI Key InChIKey=SOCABYBFBPXOQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 662069   

TargetDiacylglycerol kinase zeta(Human)
Juno Therapeutics

US Patent
LigandPNGBDBM662069(8-[(2S,5R)-4-[(4-fluorophenyl)(4-methylphenyl)meth...)
Affinity DataIC50: 320nMAssay Description:The DGKα and DGKζ reactions were performed using either extruded liposome (DGKα and DGKζ LIPGLO assays) or detergent/lipid micell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Juno Therapeutics

US Patent
LigandPNGBDBM662069(8-[(2S,5R)-4-[(4-fluorophenyl)(4-methylphenyl)meth...)
Affinity DataIC50: 670nMAssay Description:The DGKα and DGKζ reactions were performed using either extruded liposome (DGKα and DGKζ LIPGLO assays) or detergent/lipid micell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent