BDBM662078 US20240108654, Compound 19

SMILES CC[C@@H]1CN([C@@H](C)CN1[C@@H](C)c1ccc(cc1)C(F)(F)F)c1nc(=O)n(C)c2ccc(nc12)C#N

InChI Key InChIKey=AIVDFWPDLDQNIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 662078   

TargetDiacylglycerol kinase alpha(Human)
Juno Therapeutics

US Patent
LigandPNGBDBM662078(US20240108654, Compound 19)
Affinity DataIC50: 390nMAssay Description:The DGKα and DGKζ reactions were performed using either extruded liposome (DGKα and DGKζ LIPGLO assays) or detergent/lipid micell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Juno Therapeutics

US Patent
LigandPNGBDBM662078(US20240108654, Compound 19)
Affinity DataIC50: 810nMAssay Description:The DGKα and DGKζ reactions were performed using either extruded liposome (DGKα and DGKζ LIPGLO assays) or detergent/lipid micell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent