BDBM662273 1-((6-(3- aminopyrrolidin-1- yl)pyridin-3-yl)methyl)- 3-(4-(2-(4- methoxyphenyl)propan- 2-yl)thiazol-2-yl)urea::US20240109853, Compound A186::US20240109853, Compound A199::US20240226094, Compound A199
SMILES COc1ccc(cc1)C(C)(C)c1csc(NC(=O)NCc2ccc(nc2)N2CCC(N)C2)n1
InChI Key InChIKey=KHJDOQFZFBYJBK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 662273
Affinity DataIC50: 19nMAssay Description:In brief, dose-response studies were performed in 384-well assay plates. Each well contained 0.1 mg TIFA, ALPK1 (2 nM final concentration in reaction...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:ALPK1 kinase activity was measured in an in vitro assay using ADP-Heptose as the ALPK1 ligand and activator of its kinase activity and TIFA protein a...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:In brief, dose-response studies were performed in 384-well assay plates. Each well contained 0.1 mg TIFA, ALPK1 (2 nM final concentration in reaction...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:ALPK1 kinase activity was measured in an in vitro assay using ADP-Heptose as the ALPK1 ligand and activator of its kinase activity and TIFA protein a...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair