BDBM662526 N-(4-(2-(4- bromophenyl)-1- methoxypropan-2- yl)thiazol-2-yl)-2,6- difluoro-4-(piperazin- 1-yl)benzamide::US20240109853, Compound C014::US20240109853, Compound C027::US20240226094, Compound C027
SMILES COCC(C)(c1csc(NC(=O)c2c(F)cc(cc2F)N2CCNCC2)n1)c1ccc(Br)cc1
InChI Key InChIKey=PVIRDZUJCCQSKY-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 662526
Affinity DataIC50: 13nMAssay Description:In brief, dose-response studies were performed in 384-well assay plates. Each well contained 0.1 mg TIFA, ALPK1 (2 nM final concentration in reaction...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:ALPK1 kinase activity was measured in an in vitro assay using ADP-Heptose as the ALPK1 ligand and activator of its kinase activity and TIFA protein a...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:ALPK1 kinase activity was measured in an in vitro assay using ADP-Heptose as the ALPK1 ligand and activator of its kinase activity and TIFA protein a...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:In brief, dose-response studies were performed in 384-well assay plates. Each well contained 0.1 mg TIFA, ALPK1 (2 nM final concentration in reaction...More data for this Ligand-Target Pair