BDBM662787 5-[(1R)-1-(3,5-dichloro-2- methyl-4-pyridyl)ethoxy]-3-[6- (3-methoxy-3-methyl-azetidin- 1-yl)-3-pyridyl]-1H-indazole::US20240109865, Example 210.

SMILES COC1(C)CN(C1)c1ccc(cn1)-c1n[nH]c2ccc(O[C@H](C)c3c(Cl)cnc(C)c3Cl)cc12

InChI Key InChIKey=MHVVHNGLZHSECI-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 662787   

TargetFibroblast growth factor receptor 4(Human)
Tyra Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 662787BDBM662787(US20240109865, Example 210. | 5-[(1R)-1-(3,5-dichl...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Tyra Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 662787BDBM662787(US20240109865, Example 210. | 5-[(1R)-1-(3,5-dichl...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetFibroblast growth factor receptor 3 [V555M](Human)
Tyra Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 662787BDBM662787(US20240109865, Example 210. | 5-[(1R)-1-(3,5-dichl...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Tyra Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 662787BDBM662787(US20240109865, Example 210. | 5-[(1R)-1-(3,5-dichl...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Tyra Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 662787BDBM662787(US20240109865, Example 210. | 5-[(1R)-1-(3,5-dichl...)
Affinity DataKd:  60nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent