BDBM662951 US20240109877, Example 5

SMILES C[C@@H](NC(=O)c1nc(no1)C(C)(C)C)c1ccc(cc1C)-c1cc(Nc2ccc(cn2)N2CCN(CCc3ccc(N4CCC(=O)NC4=O)c(F)c3)C[C@H]2C)ncn1

InChI Key InChIKey=XZWLTIJDAOOAOZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 662951   

LigandPNGBDBM662951(US20240109877, Example 5 | US20250304568, Example ...)
Affinity DataIC50: 0.113nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM662951(US20240109877, Example 5 | US20250304568, Example ...)
Affinity DataIC50: 0.113nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetProtein cereblon(Human)TBA
LigandPNGBDBM662951(US20240109877, Example 5 | US20250304568, Example ...)
Affinity DataIC50: 648nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProtein cereblon(Human)TBA
LigandPNGBDBM662951(US20240109877, Example 5 | US20250304568, Example ...)
Affinity DataIC50: 648nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent