BDBM662962 US20240109877, Example 16
SMILES C[C@@H](NC(=O)c1nc(no1)C(C)(C)C)c1ccc(cc1C(F)(F)F)-c1cc(Nc2ccc(cn2)N2CCN(CCc3ccc(cc3)N3CCC(=O)NC3=O)C[C@@H]2C)ncn1
InChI Key InChIKey=FBCKBVQQCMIWBW-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 662962
Affinity DataIC50: 0.438nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
Affinity DataIC50: 0.438nMAssay Description:Specifically the following was added: (1) compound buffer or control: 5 μL of 5× compound buffer [(5× compound buffer comprised of: 1× Master Buffer,...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus #600...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair