BDBM663470 ((1S,6R,7R)-7-(3,5-difluorophenyl)-3-(3-(2,4- dimethyl-2H-indazol-5-yl)-1H-pyrazolo[3,4- b]pyrazin-6-yl)-3-azabicyclo[4.1.0]heptan-7- yl)methanamine::US20240109900, Example 308

SMILES Cc1c(ccc2nn(C)cc12)-c1n[nH]c2nc(cnc12)N1CC[C@@H]2[C@H](C1)[C@@]2(CN)c1cc(F)cc(F)c1

InChI Key InChIKey=GVBMIARLAYIMSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663470   

LigandPNGBDBM663470(((1S,6R,7R)-7-(3,5-difluorophenyl)-3-(3-(2,4- dime...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent