BDBM663471 ((1S,6R,7R)-7-(2-fluorophenyl)-3-(3-(2- (trifluoromethyl)quinazolin-6-yl)-1H-pyrazolo[3,4- b]pyrazin-6-yl)-3-azabicyclo[4.1.0]heptan-7- yl)methanamine::US20240109900, Example 309

SMILES NC[C@@]1([C@@H]2CCN(C[C@H]12)c1cnc2c(n[nH]c2n1)-c1ccc2nc(ncc2c1)C(F)(F)F)c1ccccc1F

InChI Key InChIKey=BEKBQEKGCVCBTD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663471   

LigandPNGBDBM663471(((1S,6R,7R)-7-(2-fluorophenyl)-3-(3-(2- (trifluoro...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent