BDBM663473 ((1S,6R,7R)-3-(3-(5-chloro-3,4-dihydro-2H- benzo[b][1,4]oxazin-6-yl)-1,7-dihydro-412- pyrazolo[4,3-b]pyrazin-6-yl)-7-(2-fluorophenyl)-3- azabicyclo[4.1.0]heptan-7-yl)methanamine::US20240109900, Example 311

SMILES NC[C@@]1([C@@H]2CCN(C[C@H]12)c1cnc2c(n[nH]c2n1)-c1ccc2OCCNc2c1Cl)c1ccccc1F

InChI Key InChIKey=HSHCTSHTOFHAIT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663473   

LigandPNGBDBM663473(((1S,6R,7R)-3-(3-(5-chloro-3,4-dihydro-2H- benzo[b...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent