BDBM663479 5-(6-((1S,6R,7R)-7-(aminomethyl)-7-(2- fluorophenyl)-3-azabicyclo[4.1.0]heptan-3-yl)-1H- pyrazolo[3,4-b]pyrazin-3-yl)-4-chloro-1,3-dimethyl- 1,3-dihydro-2H-benzo[d]imidazol-2-one::US20240109900, Example 317

SMILES Cn1c2ccc(-c3n[nH]c4nc(cnc34)N3CC[C@@H]4[C@H](C3)[C@@]4(CN)c3ccccc3F)c(Cl)c2n(C)c1=O

InChI Key InChIKey=FBLOPUIRJMVSKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663479   

LigandPNGBDBM663479(5-(6-((1S,6R,7R)-7-(aminomethyl)-7-(2- fluoropheny...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent