BDBM663480 ((1S,6R,7R)-3-(3-(1,4-dimethyl-4,7-dihydro-1H- benzo[d]imidazol-5-yl)-1H-pyrazolo[3,4-b]pyrazin-6- yl)-7-(2-fluorophenyl)-3-azabicyclo[4.1.0]heptan-7- yl)methanamine::US20240109900, Example 318

SMILES Cc1c(ccc2n(C)cnc12)-c1n[nH]c2nc(cnc12)N1CC[C@@H]2[C@H](C1)[C@@]2(CN)c1ccccc1F

InChI Key InChIKey=AXEMUNCWBOFSCM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663480   

LigandPNGBDBM663480(((1S,6R,7R)-3-(3-(1,4-dimethyl-4,7-dihydro-1H- ben...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent