BDBM663483 ((1S,6R,7R)-3-(3-(5-chloro-4-methyl-3,4-dihydro- 2H-benzo[b][1,4]oxazin-6-yl)-2,3,4,7-tetrahydro-1H- pyrazolo[3,4-b]pyrazin-6-yl)-7-(2-fluorophenyl)-3- azabicyclo[4.1.0]heptan-7-yl)methanamine::US20240109900, Example 321

SMILES CN1CCOc2ccc(-c3n[nH]c4nc(cnc34)N3CC[C@@H]4[C@H](C3)[C@@]4(CN)c3ccccc3F)c(Cl)c12

InChI Key InChIKey=XWICUXTZOHUXEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663483   

LigandPNGBDBM663483(((1S,6R,7R)-3-(3-(5-chloro-4-methyl-3,4-dihydro- 2...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent