BDBM663491 ((1S,6R,7R)-3-(3-(4-chloro-1-methyl-1H- benzo[d]imidazol-5-yl)-1H-pyrazolo[3,4-b]pyrazin-6- yl)-7-(2-fluorophenyl)-3-azabicyclo[4.1.0]heptan-7- yl)methanamine::US20240109900, Example 329

SMILES Cn1cnc2c(Cl)c(ccc12)-c1n[nH]c2nc(cnc12)N1CC[C@@H]2[C@H](C1)[C@@]2(CN)c1ccccc1F

InChI Key InChIKey=GAWMMBVVMUNBEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663491   

LigandPNGBDBM663491(((1S,6R,7R)-3-(3-(4-chloro-1-methyl-1H- benzo[d]im...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent