BDBM663492 ((1S,6R,7R)-3-(3-(3,5-difluorophenyl)-1H- pyrazolo[3,4-b]pyrazin-6-yl)-7-(2-fluorophenyl)-3- azabicyclo[4.1.0]heptan-7-yl)methanamine::US20240109900, Example 330

SMILES NC[C@@]1([C@@H]2CCN(C[C@H]12)c1cnc2c(n[nH]c2n1)-c1cc(F)cc(F)c1)c1ccccc1F

InChI Key InChIKey=FPRPFLKMLKDZOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663492   

LigandPNGBDBM663492(((1S,6R,7R)-3-(3-(3,5-difluorophenyl)-1H- pyrazolo...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent