BDBM663505 5-(6-((1S,6R,7R)-7-(aminomethyl)-7-(2- fluorophenyl)-3-azabicyclo[4.1.0]heptan-3-yl)-5- methyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4- d]pyrimidin-3-yl)quinoline-8-carboxamide::US20240109900, Example 343

SMILES Cn1c(nc2[nH]nc(-c3ccc(C(N)=O)c4ncccc34)c2c1=O)N1CC[C@@H]2[C@H](C1)[C@@]2(CN)c1ccccc1F

InChI Key InChIKey=WHGUGDUWGAGAMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663505   

LigandPNGBDBM663505(5-(6-((1S,6R,7R)-7-(aminomethyl)-7-(2- fluoropheny...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent