BDBM663506 6-((1S,6R,7R)-7-(aminomethyl)-7-(3,5- difluorophenyl)-3-azabicyclo[4.1.0]heptan-3-yl)-3-(4- chloro-2-methyl-2H-indazol-5-yl)-5-methyl-1,5- dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one::US20240109900, Example 344

SMILES Cn1cc2c(Cl)c(ccc2n1)-c1n[nH]c2nc(N3CC[C@@H]4[C@H](C3)[C@@]4(CN)c3cc(F)cc(F)c3)n(C)c(=O)c12

InChI Key InChIKey=QUMVNUDNXBBUJG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663506   

LigandPNGBDBM663506(6-((1S,6R,7R)-7-(aminomethyl)-7-(3,5- difluorophen...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent