BDBM663518 4-(6-((1S,6R,7R)-7-(aminomethyl)-7-(2- fluorophenyl)-3-azabicyclo[4.1.0]heptan-3-yl)-1H- pyrazolo[3,4-b]pyrazin-3-yl)-3-chloro-N-cyano-N- methylbenzamide::US20240109900, Example 356

SMILES CN(C#N)C(=O)c1ccc(-c2n[nH]c3nc(cnc23)N2CC[C@@H]3[C@H](C2)[C@@]3(CN)c2ccccc2F)c(Cl)c1

InChI Key InChIKey=DJHBNLILTRCDSJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663518   

LigandPNGBDBM663518(4-(6-((1S,6R,7R)-7-(aminomethyl)-7-(2- fluoropheny...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent