BDBM663519 6-(6-((1S,6R,7R)-7-(aminomethyl)-7-(2- fluorophenyl)-3-azabicyclo[4.1.0]heptan-3-yl)- 114,712-pyrazolo[5,4-b]pyrazin-3-yl)-5-fluoro-2-(2- methoxyethyl)isoquinolin-1(2H)-one::US20240109900, Example 357

SMILES COCCn1ccc2c(F)c(ccc2c1=O)-c1n[nH]c2nc(cnc12)N1CC[C@@H]2[C@H](C1)[C@@]2(CN)c1ccccc1F

InChI Key InChIKey=JJDBIHSQLWKVTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663519   

LigandPNGBDBM663519(6-(6-((1S,6R,7R)-7-(aminomethyl)-7-(2- fluoropheny...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent