BDBM663520 ((1S,6R,7R)-3-(3-(4-chloro-2,3-dimethyl-2,3- dihydro-1H-benzo[d]imidazol-5-yl)-1H-pyrazolo[3,4- b]pyrazin-6-yl)-7-(2-fluorophenyl)-3- azabicyclo[4.1.0]heptan-7-yl)methanamine::US20240109900, Example 358

SMILES Cc1nc2ccc(-c3n[nH]c4nc(cnc34)N3CC[C@@H]4[C@H](C3)[C@@]4(CN)c3ccccc3F)c(Cl)c2n1C

InChI Key InChIKey=HROCKCCPXQFFMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663520   

LigandPNGBDBM663520(((1S,6R,7R)-3-(3-(4-chloro-2,3-dimethyl-2,3- dihyd...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent