BDBM663531 ((1S,6R,7R)-3-(3-(4-chloro-2-methyl-2H-indazol-5- yl)-1H-pyrazolo[3,4-b]pyrazin-6-yl)-7-(2,5- difluorophenyl)-3-azabicyclo[4.1.0]heptan-7- yl)methanamine::US20240109900, Example 369

SMILES Cn1cc2c(Cl)c(ccc2n1)-c1n[nH]c2nc(cnc12)N1CC[C@@H]2[C@H](C1)[C@@]2(CN)c1cc(F)ccc1F

InChI Key InChIKey=PXQFVQQIDJQFMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663531   

LigandPNGBDBM663531(((1S,6R,7R)-3-(3-(4-chloro-2-methyl-2H-indazol-5- ...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent