BDBM663532 6-(6-((1S,6R,7R)-7-(aminomethyl)-7-(2- fluorophenyl)-3-azabicyclo[4.1.0]heptan-3-yl)-1H- pyrazolo[3,4-b]pyrazin-3-yl)-7-chloroisoquinolin- 1(2H)-one::US20240109900, Example 370

SMILES NC[C@@]1([C@@H]2CCN(C[C@H]12)c1cnc2c(n[nH]c2n1)-c1cc2cc[nH]c(=O)c2cc1Cl)c1ccccc1F

InChI Key InChIKey=GSXBTTYYIIDYPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663532   

LigandPNGBDBM663532(6-(6-((1S,6R,7R)-7-(aminomethyl)-7-(2- fluoropheny...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent