BDBM663797 US20240109912, Compound 130

SMILES CC#CC(=O)N1CC[C@H](C1)N1CC(C1)c1cc(C)c2O[C@H](C)c3c(Nc2c1)ncnc3N1CCS(=O)(=O)CC1

InChI Key InChIKey=IRYADJLUIMPLBE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 663797   

TargetCyclin-dependent kinase 7(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM663797(US20240109912, Compound 130)
Affinity DataKi:  0.0570nMAssay Description:CDK7 activity is measured by following the production of ADP generated from ATP-dependent phosphorylation of the peptide substrate derived from RNA P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM663797(US20240109912, Compound 130)
Affinity DataKi:  0.117nMAssay Description:CDK7 activity is measured by following the production of ADP generated from ATP-dependent phosphorylation of the peptide substrate derived from RNA P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM663797(US20240109912, Compound 130)
Affinity DataKi:  0.117nMAssay Description:CDK7 activity is measured by following the production of ADP generated from ATP-dependent phosphorylation of the peptide substrate derived from RNA P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent