BDBM664607 4-(1-((2R,3R,4S,5R,6R)-2-((1-(1-(difluoromethyl)cyclobutyl)-1H-1,2,3- triazol-4-yl)methyl)-5-hydroxy-6-(hydroxymethyl)-3-methoxytetrahydro- 2H-pyran-4-yl)-1H-1,2,3-triazol-4-yl)-2,3-difluorobenzonitrile::US20240109930, Example 5.1.43.

SMILES COC1=C(C(O)=C(CO)O[C@@H]1C[C@H]1CN(NN1)C1(CCC1)C(F)F)n1cc(nn1)-c1ccc(C#N)c(F)c1F

InChI Key InChIKey=XMGZNGQHBCFGFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 664607   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM664607(4-(1-((2R,3R,4S,5R,6R)-2-((1-(1-(difluoromethyl)cy...)
Affinity DataIC50: 30nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384well plates are supplemented with 22.8 μL/well of biotinylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM664607(4-(1-((2R,3R,4S,5R,6R)-2-((1-(1-(difluoromethyl)cy...)
Affinity DataIC50: 1.32E+3nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384well plates are supplemented with 22.8 μL/well of biotinylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent