BDBM664608 2,3-difluoro-4-(1-((2R,3R,4S,5R,6R)-2-((1-((3R*,4S*)-3-fluorotetrahydro-2H-pyran-4-yl)-1H-1,2,3-triazol-4-yl)methyl)-5-hydroxy-6-(hydroxymethyl)-3-methoxytetrahydro-2H-pyran-4-yl)-1H-1,2,3-triazol-4-yl)benzonitrile::US20240109930, Example 5.1.66.CD

SMILES CO[C@H]1[C@@H](Cc2cn(nn2)[C@H]2CCOC[C@@H]2F)O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(C#N)c(F)c1F

InChI Key InChIKey=UTYBQOWJQKMVSR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 664608   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM664608(2,3-difluoro-4-(1-((2R,3R,4S,5R,6R)-2-((1-((3R*,4S...)
Affinity DataIC50: 30nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384well plates are supplemented with 22.8 μL/well of biotinylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM664608(2,3-difluoro-4-(1-((2R,3R,4S,5R,6R)-2-((1-((3R*,4S...)
Affinity DataIC50: 1.60E+3nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384well plates are supplemented with 22.8 μL/well of biotinylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent