BDBM664674 US11952364, Example 12

SMILES COc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1

InChI Key InChIKey=HYNGNWCMHJYQRN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 664674   

TargetCytochrome P450 2C9(Human)
TYLIGAND BIOSCIENCE (SHANGHAI) LIMITED

US Patent
LigandPNGBDBM664674(US11952364, Example 12)
Affinity DataIC50: 9.80E+3nMAssay Description:Human liver microsome solution prepared according to the following table (diluted with potassium phosphate solution) Protein con. of working Final pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2024
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
TYLIGAND BIOSCIENCE (SHANGHAI) LIMITED

US Patent
LigandPNGBDBM664674(US11952364, Example 12)
Affinity DataIC50: 1.00E+4nMAssay Description:Human liver microsome solution prepared according to the following table (diluted with potassium phosphate solution) Protein con. of working Final pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2024
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
TYLIGAND BIOSCIENCE (SHANGHAI) LIMITED

US Patent
LigandPNGBDBM664674(US11952364, Example 12)
Affinity DataIC50: 1.00E+4nMAssay Description:Human liver microsome solution prepared according to the following table (diluted with potassium phosphate solution) Protein con. of working Final pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2024
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
TYLIGAND BIOSCIENCE (SHANGHAI) LIMITED

US Patent
LigandPNGBDBM664674(US11952364, Example 12)
Affinity DataIC50: 1.00E+4nMAssay Description:Human liver microsome solution prepared according to the following table (diluted with potassium phosphate solution) Protein con. of working Final pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2024
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
TYLIGAND BIOSCIENCE (SHANGHAI) LIMITED

US Patent
LigandPNGBDBM664674(US11952364, Example 12)
Affinity DataIC50: 1.00E+4nMAssay Description:Human liver microsome solution prepared according to the following table (diluted with potassium phosphate solution) Protein con. of working Final pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2024
Entry Details
US Patent