BDBM664684 US11952377, Example 12

SMILES Cn1c2ccc(cc2c(N[C@H]2CC[C@@H](CC2)C(C)(C)O)cc1=O)-n1ccnc1

InChI Key InChIKey=XBPIKYGSPGGDPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 664684   

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM664684(US11952377, Example 12)
Affinity DataIC50: 55nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2024
Entry Details
US Patent