BDBM664689 US11952377, Example 17

SMILES CN(C)CCOc1ccc(Nc2cc(=O)n(C)c3ccc(cc23)-n2ccnc2)cn1

InChI Key InChIKey=AEVUSHITPSDVGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 664689   

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM664689(US11952377, Example 17)
Affinity DataIC50: 55nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
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Date in BDB:
6/27/2024
Entry Details
US Patent