BDBM665743 US20240116922, Example 45

SMILES CC(C)Oc1nc2nc(cn2cc1C(=O)Nc1cccn(C2CC2)c1=O)C12CCC(CF)(C1)OC2

InChI Key InChIKey=VSHPJHJXADWNDG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665743   

TargetInterleukin-1 receptor-associated kinase 4(Human)
BIOGEN MA INC.

US Patent
LigandPNGBDBM665743(US20240116922, Example 45)
Affinity DataIC50:  0.200nMAssay Description:The 2-hour 1 mM ATP Biochemical Assay employed a MesoScale Detection (MSD) format. The kinase reaction was based on the IRAK4 phosphorylation of a bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent