BDBM665874 US20240116922, Example 176

SMILES CC(C)Oc1nc2nc(cn2cc1C(=O)Nc1cccn([C@@H]2C[C@@H]2F)c1=O)[C@]12CC[C@](C)(C1)OC2

InChI Key InChIKey=BQWJRRHYDCRKIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665874   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM665874(US20240116922, Example 176)
Affinity DataIC50: 0.300nMAssay Description:The 2-hour 1 mM ATP Biochemical Assay employed a MesoScale Detection (MSD) format. The kinase reaction was based on the IRAK4 phosphorylation of a bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent