BDBM665948 US20240116926, Example 35

SMILES O[C@H]1CN(C[C@H]1Nc1ncc(-c2ccc(cn2)C(F)(F)F)c2ncccc12)C(=O)C=C

InChI Key InChIKey=XMCMLALZSBBAJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665948   

TargetTranscriptional enhancer factor TEF-3 [217-434](Human)
Astrazeneca

US Patent
LigandPNGBDBM665948(US20240116926, Example 35)
Affinity DataIC50: 79nMAssay Description:Compound IC50 values were assessed following a 10-point, half-log10 dilution schema starting at 100 μM compound concentration. Specifically, hum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent