BDBM667070 N-{4-[7-(5-chloro-2-fluorophenyl)- 1H,2H,3H- pyrido[3,4-b][1,4]oxazin-1- yl]pyridin-2-yl}-3- (dimethylamino)propanamide::US20240116947, Example 9

SMILES CN(C)CCC(=O)Nc1cc(ccn1)N1CCOc2cnc(cc12)-c1cc(Cl)ccc1F

InChI Key InChIKey=SYRWBTHLWMKVJQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667070   

TargetTGF-beta receptor type-1(Human)
CHIESI FARMACEUTICI S.P.A.

US Patent
LigandPNGBDBM667070(N-{4-[7-(5-chloro-2-fluorophenyl)- 1H,2H,3H- pyrid...)
Affinity DataIC50: <1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent