BDBM667158 2-methyl-6-(8-{1H-pyrazolo[3,4-b]pyridin-5-yl}-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-6-yl)pyridine::US20240116948, Example 35

SMILES Cc1cccc(n1)-c1cc(-c2cnc3[nH]ncc3c2)c2OCCNc2n1

InChI Key InChIKey=JJNNDRPPORIAMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667158   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM667158(US20240116948, Example 35 | 2-methyl-6-(8-{1H-pyra...)
Affinity DataIC50: 7.5nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent