BDBM667175 4-[7-(2-fluoro-5-methylphenyl)- 1H,2H,3H-pyrido[3,4- b][1,4]oxazin-1-yl]pyridin-2-amine::US20240116947, Example 11

SMILES Cc1ccc(F)c(c1)-c1cc2N(CCOc2cn1)c1ccnc(N)c1

InChI Key InChIKey=ZECHRNMOMPEIBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667175   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM667175(US20240116947, Example 11 | 4-[7-(2-fluoro-5-methy...)
Affinity DataIC50: 7.5nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
US Patent