BDBM667209 5-allyl-N-(3,6-dichloro-9H- xanthen-9-yl)-2-oxo-6- (trifluoromethyl)-1,2- dihydropyridine-3- carboxamide::US11957687, Compound 173

SMILES FC(F)(F)c1[nH]c(=O)c(cc1CC=C)C(=O)NC1c2ccc(Cl)cc2Oc2cc(Cl)ccc12

InChI Key InChIKey=HFROHIIJFOQQIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667209   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandPNGBDBM667209(US11957687, Compound 173 | 5-allyl-N-(3,6-dichloro...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2024
Entry Details
US Patent